In the early 1990s I was an undergraduate at Tufts, and took an exciting seminar with Dan Dennett on his manuscript that became Darwin's Dangerous Ideas. After graduation and some travel I ended up alone on a Greek Island, where captivated by the memetic theory, I wrote a very long (80 pages?) ms on how to turn memetics into a science. I sent it to Dennett and received a very kind, encouraging response. (All of this aided by Greek mail.) I went to Chicago to work with Bill Wimsatt on the science of memetics in a weekly reading group with Bill and Betty Van Meer. Bill was skeptical, but open-minded. So, we decided to focus on technology as a species of cultural evolution and try to build a science of memes out of a collection of case-studies. After relentless discussion and debate, I gave up on turning Memes into a science just as the Journal of Memetics was founded (ca 1997). Bill wrote a lovely, much cited piece about memes, and that was the end of the memetic matter for me.
So, I read the this review of a book bashing memetics with a touch of bemusement; the reviewer agrees with the book (and also bashes neo-classical economics). The following paragraph astonished me:
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